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History
The first histopathologic techniques were developed by astronomers who studied the movement of planets in the sky.
The use of special techniques (i.e., chemical reactions and specific stains) allowed them to more easily detect minute traces of substances in a sample (i.e., grains, pollen, and blood), which are termed histomorphological (internal) tissues. Histochemistry was described by the physiologist H. G. Askanase in 1852. Gregory and Staiger (1897) also reported histopathology, which was the study of changes in tissue structure. The development of histopathology was important for discovering diseases. Histopathology was a prerequisite for the development of modern microscopic techniques, such as immunohistochemistry and histochemistry. The first known use of a microscope was by the Chinese military leader Qin Shi Huang (circa. 265-210 BCE). The microscope was made to view the eye of a tiger.
The microscope was used to better observe the anatomy of the eye.
Gregorios-Bruce, J. (2007) Histopathologic techniques. Quezon City, Philippines: JMC Press.
See also
Histology
Histopathology
Histochemistry
Histochemistry
Cytochemistry
References
Gregorios-Bruce, J. H. (1974). Histopathologic techniques. New York: Springer..
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