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Today marks the National Day of Activism for Mental Illness, an annual event organized by a coalition of 19 organizations working to improve access to mental health care and end the stigma around mental illness in the United States. At the same time, there’s a new medication developed at Brown University that has shown promise in preventing a major complication of intensive care unit (ICU) care called delirium. The new intervention, known as ketamine or “K,” has been shown to be effective even for the most severe cases of delirium, and it is the first FDA-approved treatment for this condition.
Ketamine has been used in the ICU for years to treat patients who have severe psychiatric symptoms and those with intractable agitation and hallucinations. According to the ICU-Day website, over 4 million Americans with mental illness are treated in the ICU annually, and about 4.5 million people visit emergency rooms each year as a result of mental health-related issues. Individuals with mental health issues are also six times more likely to die in the hospital than those without such conditions.
The most common symptoms of delirium include an inattentive, hyperactive, or confused state. It can be provoked by a variety of conditions, such as chronic illness, advanced age, prolonged critical illness, and metabolic derangements. But the most concerning complication of delirium is that it can lead to death.
A recent study published in The New England Journal of Medicine evaluated the use of a single IV infusion of ketamine (0
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